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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1B
All Species:
4.24
Human Site:
S2045
Identified Species:
9.33
UniProt:
Q00975
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00975
NP_000709.1
2339
262496
S2045
T
P
D
R
P
P
P
S
Q
A
S
S
H
H
H
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
S2491
T
P
D
R
P
P
P
S
Q
A
S
H
H
H
H
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
N2063
R
L
S
A
H
R
L
N
S
D
S
G
H
K
S
Dog
Lupus familis
XP_537779
2046
229120
Q1756
L
D
R
A
P
A
S
Q
A
V
P
H
H
H
H
Cat
Felis silvestris
Mouse
Mus musculus
O55017
2327
261463
P2035
T
V
L
D
R
P
P
P
S
Q
A
S
H
H
H
Rat
Rattus norvegicus
Q02294
2336
262238
P2044
T
V
L
D
R
P
P
P
S
Q
V
S
H
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
D1866
I
R
D
Y
C
N
D
D
H
Y
L
G
E
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
M1539
G
N
C
G
N
P
G
M
G
I
M
F
F
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
R1561
L
A
R
S
P
S
P
R
R
R
G
H
Q
Y
I
Honey Bee
Apis mellifera
NP_001159376
1904
215872
L1614
I
Y
V
C
L
L
I
L
E
S
W
R
T
T
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
R1676
G
P
V
D
R
R
E
R
G
A
S
S
S
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
54.2
80.1
N.A.
91.9
92.1
N.A.
N.A.
38.3
N.A.
20.7
N.A.
44.7
47.6
N.A.
39.5
Protein Similarity:
100
82.3
65.5
82.2
N.A.
94.4
94.5
N.A.
N.A.
53.3
N.A.
36
N.A.
56
58.7
N.A.
52.4
P-Site Identity:
100
93.3
13.3
26.6
N.A.
46.6
46.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
13.3
0
N.A.
26.6
P-Site Similarity:
100
93.3
20
26.6
N.A.
53.3
46.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
26.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
19
0
10
0
0
10
28
10
0
0
0
0
% A
% Cys:
0
0
10
10
10
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
28
28
0
0
10
10
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
10
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% F
% Gly:
19
0
0
10
0
0
10
0
19
0
10
19
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
28
55
46
46
% H
% Ile:
19
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
19
10
19
0
10
10
10
10
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
0
10
0
0
10
10
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
28
0
0
37
46
46
19
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
19
19
0
0
10
10
0
% Q
% Arg:
10
10
19
19
28
19
0
19
10
10
0
10
0
0
19
% R
% Ser:
0
0
10
10
0
10
10
19
28
10
37
37
10
10
19
% S
% Thr:
37
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% T
% Val:
0
19
19
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _